THPEA001 Ex-vivo stimulation with HIV-1-specific antigens supports the existence of NK-cell memory-like responsePoster ExhibitionA10
THPEA002 Distinct response profiles of helper and cytotoxic innate lymphocytes during acute HIV-1 infectionPoster ExhibitionA10
THPEA003 The impact of KIR:HLA ligand genotypes in acquisition or resistance to HIV-1 clade C infection in sub-Saharan AfricaPoster ExhibitionA10
THPEA004 TLR3 agonists support the generation of a highly-functional cDC subset that is preferentially observed in cDC from HIV elite controllers after HIV-1 exposurePoster ExhibitionA10
THPEA005 Prevalence and immuno-metabolic associations of frailty in older Australian men living with HIV: a cross-sectional analysisPoster ExhibitionA11
LBPE006 Distinctive genital mucosal immune milieu in HESN Nairobi commercial sex workersPoster ExhibitionA12
THPEA006 Modulation of neutrophil gene expression and proteomic profile during acute HIV infectionPoster ExhibitionA12
TUAA0103 HIV infection is associated with preservation of MAIT cells in the lungs but alteration of their phenotype and T cell receptor repertoireOral AbstractA12
THAA0203 Neutrophils mediate potent and rapid anti-HIV antibody-dependent functionsOral AbstractA14
THAA0204 Impact of antibody isotype and association constant rate on antiviral functions against HIV-1Oral AbstractA14
THPEA007 Crystal structures of a broadly neutralizing anti-HIV antibody targeting the V2/apex epitope on HIV Env and its unmutated common ancestorPoster ExhibitionA14
THPEA008 Identification of HIV-1 MPR-directed broadly neutralizing antibodies from the acute-infection cohort RV217 subject 40512Poster ExhibitionA14
WEPDA0101 Novel mode of recognition of the glycan-V1V2 region of HIV-1 envelope by a new lineage of broadly neutralizing antibodiesPoster Discussion AbstractA14
THPEA009 Impact of HAART on activation and exhaustion of B cell subpopulations in pediatric HIV infectionPoster ExhibitionA15
THAA0202 CD8+ T cell breadth and ex vivo virus inhibition capacity distinguish between viremic controllers with and without protective HLA class I allelesOral AbstractA16
THPDA0103 CD8+ cytotoxic T lymphocytes exert a strong cytolytic effect on virally-infected cells prior to viral integration in SIVmac251-infected rhesus macaquesPoster Discussion AbstractA16
THPEA010 Impact of HIV-ART on Th17 and Treg subpopulations in blood and genital mucosaPoster ExhibitionA16
THPEA011 Modification of the HIV-specific CD8+ T cell responses in an elite controller after Chikungunya virus infectionPoster ExhibitionA16
THPEA012 Cellular immune correlates of broadly neutralising antibodies in paediatric slow progressor childrenPoster ExhibitionA16
THPEA013 Phenotypic and functional characterization of HIV-specific CD4 T cells using MHC class II tetramers in a clade C chronic HIV-1 infection cohortPoster ExhibitionA16
WEAA0104 Early treatment of hyperacute HIV infection impacts phenotype and clonal repertoire of HIV-specific CD8+ T cellsOral AbstractA16
WEPDA0102 Non-classical CD8+ T cells restricted by HLA class II emerge in HIV infection and show antiviral efficacyPoster Discussion AbstractA16
THPEA014 Mucin-binding IgG: characterizing a novel antibody effector function and discovery of a new Fc receptorPoster ExhibitionA17
THPEA015 Role of myeloid derived suppressive cells on EcoHIV evasion from vaccine induced T cell immune responsePoster ExhibitionA18
THAX0104 HIV phylogenetic analysis sheds light on transmission linkages in young women in high HIV burden districts in KwaZulu-Natal, South AfricaOral AbstractA2
THAX0105 Streamlined quasispecies and subtype analysis of HIV-1 sequences generated by high-throughput sequencing using the high-performance integrated virtual environment (HIVE)Oral AbstractA2
WEPEA001 Genetic variability of HIV-1 in the north-west of Benin, Africa: the rise of complex circulating recombinant form 30_0206 (CRF30_0206)Poster ExhibitionA2
WEPEA002 HIV-1 subtype-specific constraints on viral escape from host cellular immunityPoster ExhibitionA2
WEPEA004 Analysis of intra-patient, full length HIV gag sequences identifies regions of variabilityPoster ExhibitionA2
THPDA0105 Real time imaging of HIV uncoating in living cellsPoster Discussion AbstractA20
TUAA0105 HIV-infected patients with exceptional TCD4+ recovery during effective HAART present a distinct T CD4+ differentiation pattern, higher CD31neg naïve cells and a smaller HIV reservoirOral AbstractA20
WEPEA010 HIV-1 CRF07_BC displays slow disease progression and delayed type of viral buddingPoster ExhibitionA21
WEPEA011 Changes in Rev in HIV isolates from different clades have a significant impact on Rev/RRE functional activityPoster ExhibitionA22
WEPEA012 HIV-1 RNAs of the 1 kb class, splicing near the 3' end of the viral genome, lack coding capacity and enhance viral replication in peripheral blood mononuclear cellsPoster ExhibitionA22
WEPEA013 Metabolic dependency of HIV-1 replication: glucose and glutamine metabolism in HIV-infected primary CD4+ T cellsPoster ExhibitionA23
WEPEA014 Dependency of HIV-1 replication on and viral manipulation of the glycolytic metabolism of activated primary CD4+ T cellsPoster ExhibitionA23
WEPEA015 Exploring the role of phosphorylation as regulatory mechanism induced by HIV-1 to favor virus replicationPoster ExhibitionA23
TUPDA0104 The association of injectable progestin-only contraceptives and endogenous progestins with HIV target cell frequency in the cervix and HIV acquisition riskPoster Discussion AbstractA24
TUPEA001 RANTES, CD169/Siglec-1 and CD38-HLADR are independently associated with CXCR4-tropism in treatment naïve HIV-1 subtype C infected individualsPoster ExhibitionA24
TUPEA002 CD4+ T cell activation: a new link between intimate partner violence and HIV risk?Poster ExhibitionA24
TUPEA003 The effect of HIV-1 infection on S1P-R1 expression and function in thymocytes and their progenitors during entry into and egress from the human thymusPoster ExhibitionA25
TUPEA004 Gamma-delta T cells phenotype and activation in HIV-infected treatment- naïve patients: correlation with disease stage and immunological responsePoster ExhibitionA25
TUPEA005 Immunometabolic analysis identifies key role of hypoxia inducible factor-1 alpha (HIF-1α) in HIV-induced CD4+T cell depletionPoster ExhibitionA25
TUPEA006 Memory stem T cells and markers of mucosal immunity in the course of cARTPoster ExhibitionA25
TUAA0101 Microbial translocation during hyperacute SIV infectionOral AbstractA27
TUAA0102 Impact of a fat-rich diet on the pathogenesis of SIV infection in the African green monkey hostOral AbstractA27
TUPDA0106 The endotoxin-lipoprotein hypothesis, obesity and HIVPoster Discussion AbstractA27
TUAA0106LB Dysbiotic bacteria drive suppressive neutrophil phenotypes and prolonged lifespan in mucosal tissues of HIV-infected individualsOral AbstractA28
TUPDA0103 HIV-associated alteration in gut microbiota are associated with increased inflammation and infection of enteric CD4+ T cellsPoster Discussion AbstractA28
TUPEA007 Residual inflammation and endothelial activation in HIV-1 vertically infected children with fully suppressed viral replication on antiretroviral therapyPoster ExhibitionA29
WEAA0105LB Exhaustion of activated CD8 T cells predicts disease progression in primary HIV-1 infectionOral AbstractA29
WEPEA005 Natural variation and co-variation of the HIV-1 integrase in drug-naïve newly diagnosed HIV-1 infections in GermanyPoster ExhibitionA3
WEPEA006 Impact of Gag-protease mutations on viral fitness and drug susceptibility in HIV-1 subtype C infected patients failing a protease inhibitor inclusive treatment regimen from Durban, South AfricaPoster ExhibitionA3
THPEA016 The effects of prebiotics on microbial dysbiosis, butyrate production and immunity in HIV-infected subjectsPoster ExhibitionA30
TUPEA008 Identification of functional HIV-1 C envelope variants containing a phenylalanine residue at position 309 of the hypervariable region 3 in matched peripheral blood and cerebrospinal fluidPoster ExhibitionA32
TUPEA009 The impact of confounding factors on determination of biomarkers for neurocognitive disorders in HIV-infected subjectsPoster ExhibitionA33
TUPEA010 Association between dual TIM-3 and PD-1 expressing CD4 T cells and neurocognitive function in chronic stable HIV diseasePoster ExhibitionA33
TUPEA011 Post-treatment control or treated controllers? The impact of ART on time to viral rebound in recent seroconvertersPoster ExhibitionA36
TUPEA012 Identification of different HIV-controller phenotypes: looking for the right model of functional curePoster ExhibitionA36
TUPEA013 HIV virological controllers in an African cohortPoster ExhibitionA36
WEPDA0103 Presence of HIV-1C broadly neutralizing antibodies in pregnancy and at deliveryPoster Discussion AbstractA39
THAA0104LB No evidence of ongoing replication in tissue compartments during combination antiretroviral therapyOral AbstractA40
TUAA0104 Cell-associated HIV-1 unspliced RNA level predicts both time to virological suppression and duration of post-treatment virological control in patients treated with temporary early ARTOral AbstractA40
WEPEA016 Human cytomegalovirus latent infection modulates HIV restriction factors in CD34+ hematopoietic stem cellsPoster ExhibitionA40
TUPEA014 Identification of a new host cell HDAC complex that controls HIV latency through direct binding to the core promoterPoster ExhibitionA41
LBPE001 Whole-body SPECT in vivo imaging reveals delayed reconstitution of lymph-nodes, but not spleen, CD4 pools in long-term cART treated animalsPoster ExhibitionA42
THPDA0102 HIV persists in colon and blood CCR6+CD4+ T cells during ARTPoster Discussion AbstractA42
WEPEA017 Memory CD4+ T cells expressing HLA-DR contribute to HIV persistence during prolonged ARTPoster ExhibitionA42
WEPEA018 Is the lung a site of productive HIV infection that persists through ART?Poster ExhibitionA42
THAA0101 Frequent and 'burst-like' reactivation from latency in SIVmac239M infected macaquesOral AbstractA43
WEPEA019 Quantification and correlates of the replication competent HIV-1 latent viral reservoir in a virally suppressed Ugandan populationPoster ExhibitionA43
LBPE004 Reversal of HIV-1 latency with maraviroc alone or in combination with bryostatin-1Poster ExhibitionA44
THAA0205 T regulatory cell depletion in controller macaques reactivates SIV and boosts CTLsOral AbstractA44
THAA0206 PD-1 blockade synergizes with ART for restoring anti-viral CD8 T cell function and possibly destabilizing the viral reservoir in SIV infected macaquesOral AbstractA44
THPDA0104 Understanding the effects of latency reversing agents on HIV RNA splicing: implications for latency reversalPoster Discussion AbstractA44
THPEA017 Sirtuin1 inhibitor nicotinamide disrupts HIV-1 latencyPoster ExhibitionA44
THPEA018 Thalidomide reverses latency of HIV-1 provirusPoster ExhibitionA44
THPEA019 Targeting HSF1-mediated stress response can enhance Hsp90 inhibitor-induced suppression of HIV-1 reactivation from latencyPoster ExhibitionA44
THPEA020 A novel assay to evaluate the response of patient-derived virus to latency-reversing agents ex vivoPoster ExhibitionA44
THPEA021 Therapeutic immune recovery prevents emergence of CXCR4-tropic HIV-1Poster ExhibitionA44
THPEA022 Dendritic cells programmed by inflammatory mediators can effectively induce both the immunologic 'kick' and 'kill' of latent HIV-1Poster ExhibitionA44
TUPEA015 The influence of HLA-types on disease progression among HIV-2 infected patients in Guinea-BissauPoster ExhibitionA45
TUPEA016 Mannose binding lectin genetic polymorphism: absence of an association with HIV-1 vertical transmission in a PMTCT cross-sectional survey in ZimbabwePoster ExhibitionA45
THPEA023 Association of the chemokine stromal-derived factor-1 (SDF-1) genetic polymorphism with transaminitis in HIV-infected Thais who are on combined antiretroviral therapyPoster ExhibitionA46
THPEA024 Optimal resource allocation of a female sex workers HIV prevention interventions across districts of different size and prevalencePoster ExhibitionA46
TUPEA017 Serum estradiol level and subject age are associated with ex vivo HIV infection in human cervical tissuePoster ExhibitionA47
TUPEA018 HIV-1 constructs do not trigger macrophage inflammatory protein - 3 alpha secretion in human genital epithelial cell modelsPoster ExhibitionA47
TUPEA019 Dynamics of HIV and its target cells in the female reproductive track during acute infection and after therapyPoster ExhibitionA47
WEAA0101 Th17 cells are preferentially infected in the first 48 hours after vaginal transmission of SIVmac239 in macaquesOral AbstractA47
TUPEA020 Early reverse transcripts, an early indicator of cART efficacy in neonatal HIVPoster ExhibitionA48
WEPEA007 HIV-1 groups M+O dual infections and HIV-1/MO recombinant forms circulating in CameroonPoster ExhibitionA5
TUPDA0101 Selection of HIV-1 variants with higher transmission potential by 1% tenofovir gel microbicidePoster Discussion AbstractA50
TUPDA0102 Characterization of HIV-1 genomes from 74 acutely infected subjects in the acute infection cohort RV217Poster Discussion AbstractA50
LBPE005 Central nervous system impact of vorinostat, hydroxychloroquine and maraviroc combination therapy followed by treatment interruption in individuals treated during acute HIV infectionPoster ExhibitionA51
TUPEA021 Acute HIV-1 infection in men who have sex with men attending the clinic for voluntary counseling and testing services in Bangkok, ThailandPoster ExhibitionA51
TUPEA022 Comparison of HIV epitopes availability between acute and chronic infectionPoster ExhibitionA51
TUPEA023 Identification of a cytokine expression pattern specific for the first month of HIV infectionPoster ExhibitionA51
WEAA0103 Characterization of early events of SIVagm dissemination following intrarectal inoculation in adult AGMsOral AbstractA51
WEAA0106LB HIV Cure research in a novel population of South African hyper-acute HIV infections detected in the blood donation setting: the Monitoring and Acute Treatment of HIV Study (MATHS)Oral AbstractA51
TUPEA025 HIV pre-exposure prophylaxis for women and infants prevents vaginal and oral HIV transmission in a pre-clinical model of HIV infectionPoster ExhibitionA53
THAA0102 Excision of HIV-1 DNA by gene editing: in vitro, ex vivo and in vivo studiesOral AbstractA55
THAA0201 Novel conserved element HIV/SIV DNA vaccines maximize breadth and magnitude of immune responseOral AbstractA56
THPEA025 A novel bispecific immunoadhesin displays enhanced breadth and potency against diverse HIV-1 subtypes in vitro and in humanized micePoster ExhibitionA56
THAA0103 CCR5 gene edited cells traffic to viral reservoir tissues and undergo SHIV-dependent positive selection in nonhuman primatesOral AbstractA57
THAA0105 Allogeneic stem cell transplantation in HIV-1-infected individuals; the EPISTEM consortiumOral AbstractA57
THAA0106LB Elimination of HIV-1 latently infected cells by PKC agonist gnidimacrin alone and in combination with a histone deacetylase inhibitorOral AbstractA57
WEPEA020 Therapy with the immunomodulatory agent pomalidomide does not lead to changes in HIV-1 viral populations in vivoPoster ExhibitionA57
WEPEA021 Novel pathways of Tat expression identify new targets for reactivation of latent HIV-1Poster ExhibitionA57
WEPEA022 Combinatorial CRISPR/Cas9 approaches targeting different steps in the HIV life cycle can prevent the selection of resistancePoster ExhibitionA57
WEPEA023 Enhancing HIV-1 virion tethering by BST2/tetherin sensitizes productively and latently infected T cells to ADCC mediated by broadly neutralizing anti-HIV antibodiesPoster ExhibitionA57
WEPEA024 Small molecule inhibitors of BAF: a new family of compounds in HIV-1 latency reversalPoster ExhibitionA57
WEPEA025 Novel activators and suppressors of latent HIV-1 from natural productsPoster ExhibitionA57
WEPEA026 Heterodimeric IL-15 induces effector cell activation and trafficking to the Germinal Centers of SIV infected MacaquesPoster ExhibitionA57
THPEA026 Evolution of cross-neutralizing antibodies and mapping epitope specificities in plasma of chronic HIV-1 infected ART naïve children from IndiaPoster ExhibitionA58
THPEA027 Molecular characteristics and use of bovine IgG with broad HIV-1 neutralizing activity from colostrum of cows vaccinated with Env-gp140 trimersPoster ExhibitionA58
WEPDA0105 Human sPD1-based HIV-1 gag-fusion DNA vaccine induces high frequency of broadly reactive T cell responses in mice and rhesus macaquesPoster Discussion AbstractA59
THPEA028 Intranasal vaccination with a live recombinant rhinovirus and a DNA boost elicits HIV-specific immunity that controls EcoHIV infection in micePoster ExhibitionA61
THPEA029 HIV-tat fused to the oligomerisation domain of the c4-binding protein is highly immunogenic and controls EcoHIV challenge in micePoster ExhibitionA62
TUPEA026 Evaluation of the loop-mediated isothermal amplification (LAMP) assay for the detection of M. tuberculosis (TB) in symptomatic tuberculosis patients attending a primary healthcare clinic (PHC) in DurbanPoster ExhibitionA66
TUPDA0105 The mechanisms and role of HPV in enhancing HIV transmission in women in South AfricaPoster Discussion AbstractA68
TUPEA027 High-risk human papillomavirus types in HIV-infected and uninfected young women in a cross-sectional study in KwaZulu Natal, South Africa: implications for vaccinationPoster ExhibitionA68
WEPEA027 Multisite evaluation of the BD FACSPresto? CD4 counterPoster ExhibitionA69
WEPEA028 Pilot assessment of the diagnostic accuracy of Cepheid GeneXpert HIV-1 Qual for early infant diagnosisPoster ExhibitionA69
WEAA0102 Effect of injectable hormonal contraceptives on vaginal epithelium thickness and genital HIV target cell density in women recently infected with HIVOral AbstractA7
THPEA030 Introducing the new fully-automated volumetric Aquios flow cytometer PanLeucogate (PLG) platform for CD4-T lymphocyte enumeration in South Africa. Part I: establishing instrument precision and accuracyPoster ExhibitionA70
TUPEA028 Transcriptome analysis of differentially expressed ISG subsets in acute and chronic phase suggests INFg participate in sustaining persistent ISG expression in pathogenic SIV infection in cynomolgus macaquesPoster ExhibitionA75
TUPEA029 PNS inflammation during acute SIVPoster ExhibitionA75
LBPE002 A nonhuman primate model of fully MHC-matched allogeneic stem cell transplantation to study HIV reservoir clearancePoster ExhibitionA76
TUPEA030 Distribution and localization of fluorescently tagged passively transferred antibodies: defining antibody dynamics and localization in vivoPoster ExhibitionA76
THPDA0101 Immuno-PET/CT imaging reveals differences in virus and CD4+ cell localization in SIV infected rhesus macaques treated with an anti-α4β7 mabPoster Discussion AbstractA77
LBPE003 Non-human TRIM5 variants enhance recognition of HIV-1-infected cells by CD8+ T cellsPoster ExhibitionA8
WEPDA0104 PML/TRIM19-dependent inhibition of retroviral reverse-transcription by DaxxPoster Discussion AbstractA8
WEPEA008 Interferon-induced sterile alpha motif and histidine/aspartic acid domain-containing protein 1 (SAMHD1) expression is mediated by miR-181aPoster ExhibitionA8
WEPEA009 Endogenous TRIM5a function is regulated by SUMOylation and nuclear sequestration for efficient innate sensing in dendritic cellsPoster ExhibitionA8