LBPE001 | Whole-body SPECT in vivo imaging reveals delayed reconstitution of lymph-nodes, but not spleen, CD4 pools in long-term cART treated animals | Poster Exhibition | A42 |
LBPE002 | A nonhuman primate model of fully MHC-matched allogeneic stem cell transplantation to study HIV reservoir clearance | Poster Exhibition | A76 |
LBPE003 | Non-human TRIM5 variants enhance recognition of HIV-1-infected cells by CD8+ T cells | Poster Exhibition | A8 |
LBPE004 | Reversal of HIV-1 latency with maraviroc alone or in combination with bryostatin-1 | Poster Exhibition | A44 |
LBPE005 | Central nervous system impact of vorinostat, hydroxychloroquine and maraviroc combination therapy followed by treatment interruption in individuals treated during acute HIV infection | Poster Exhibition | A51 |
LBPE006 | Distinctive genital mucosal immune milieu in HESN Nairobi commercial sex workers | Poster Exhibition | A12 |
THAA0101 | Frequent and 'burst-like' reactivation from latency in SIVmac239M infected macaques | Oral Abstract | A43 |
THAA0102 | Excision of HIV-1 DNA by gene editing: in vitro, ex vivo and in vivo studies | Oral Abstract | A55 |
THAA0103 | CCR5 gene edited cells traffic to viral reservoir tissues and undergo SHIV-dependent positive selection in nonhuman primates | Oral Abstract | A57 |
THAA0104LB | No evidence of ongoing replication in tissue compartments during combination antiretroviral therapy | Oral Abstract | A40 |
THAA0105 | Allogeneic stem cell transplantation in HIV-1-infected individuals; the EPISTEM consortium | Oral Abstract | A57 |
THAA0106LB | Elimination of HIV-1 latently infected cells by PKC agonist gnidimacrin alone and in combination with a histone deacetylase inhibitor | Oral Abstract | A57 |
THAA0201 | Novel conserved element HIV/SIV DNA vaccines maximize breadth and magnitude of immune response | Oral Abstract | A56 |
THAA0202 | CD8+ T cell breadth and ex vivo virus inhibition capacity distinguish between viremic controllers with and without protective HLA class I alleles | Oral Abstract | A16 |
THAA0203 | Neutrophils mediate potent and rapid anti-HIV antibody-dependent functions | Oral Abstract | A14 |
THAA0204 | Impact of antibody isotype and association constant rate on antiviral functions against HIV-1 | Oral Abstract | A14 |
THAA0205 | T regulatory cell depletion in controller macaques reactivates SIV and boosts CTLs | Oral Abstract | A44 |
THAA0206 | PD-1 blockade synergizes with ART for restoring anti-viral CD8 T cell function and possibly destabilizing the viral reservoir in SIV infected macaques | Oral Abstract | A44 |
THAX0104 | HIV phylogenetic analysis sheds light on transmission linkages in young women in high HIV burden districts in KwaZulu-Natal, South Africa | Oral Abstract | A2 |
THAX0105 | Streamlined quasispecies and subtype analysis of HIV-1 sequences generated by high-throughput sequencing using the high-performance integrated virtual environment (HIVE) | Oral Abstract | A2 |
THPDA0101 | Immuno-PET/CT imaging reveals differences in virus and CD4+ cell localization in SIV infected rhesus macaques treated with an anti-α4β7 mab | Poster Discussion Abstract | A77 |
THPDA0102 | HIV persists in colon and blood CCR6+CD4+ T cells during ART | Poster Discussion Abstract | A42 |
THPDA0103 | CD8+ cytotoxic T lymphocytes exert a strong cytolytic effect on virally-infected cells prior to viral integration in SIVmac251-infected rhesus macaques | Poster Discussion Abstract | A16 |
THPDA0104 | Understanding the effects of latency reversing agents on HIV RNA splicing: implications for latency reversal | Poster Discussion Abstract | A44 |
THPDA0105 | Real time imaging of HIV uncoating in living cells | Poster Discussion Abstract | A20 |
THPEA001 | Ex-vivo stimulation with HIV-1-specific antigens supports the existence of NK-cell memory-like response | Poster Exhibition | A10 |
THPEA002 | Distinct response profiles of helper and cytotoxic innate lymphocytes during acute HIV-1 infection | Poster Exhibition | A10 |
THPEA003 | The impact of KIR:HLA ligand genotypes in acquisition or resistance to HIV-1 clade C infection in sub-Saharan Africa | Poster Exhibition | A10 |
THPEA004 | TLR3 agonists support the generation of a highly-functional cDC subset that is preferentially observed in cDC from HIV elite controllers after HIV-1 exposure | Poster Exhibition | A10 |
THPEA005 | Prevalence and immuno-metabolic associations of frailty in older Australian men living with HIV: a cross-sectional analysis | Poster Exhibition | A11 |
THPEA006 | Modulation of neutrophil gene expression and proteomic profile during acute HIV infection | Poster Exhibition | A12 |
THPEA007 | Crystal structures of a broadly neutralizing anti-HIV antibody targeting the V2/apex epitope on HIV Env and its unmutated common ancestor | Poster Exhibition | A14 |
THPEA008 | Identification of HIV-1 MPR-directed broadly neutralizing antibodies from the acute-infection cohort RV217 subject 40512 | Poster Exhibition | A14 |
THPEA009 | Impact of HAART on activation and exhaustion of B cell subpopulations in pediatric HIV infection | Poster Exhibition | A15 |
THPEA010 | Impact of HIV-ART on Th17 and Treg subpopulations in blood and genital mucosa | Poster Exhibition | A16 |
THPEA011 | Modification of the HIV-specific CD8+ T cell responses in an elite controller after Chikungunya virus infection | Poster Exhibition | A16 |
THPEA012 | Cellular immune correlates of broadly neutralising antibodies in paediatric slow progressor children | Poster Exhibition | A16 |
THPEA013 | Phenotypic and functional characterization of HIV-specific CD4 T cells using MHC class II tetramers in a clade C chronic HIV-1 infection cohort | Poster Exhibition | A16 |
THPEA014 | Mucin-binding IgG: characterizing a novel antibody effector function and discovery of a new Fc receptor | Poster Exhibition | A17 |
THPEA015 | Role of myeloid derived suppressive cells on EcoHIV evasion from vaccine induced T cell immune response | Poster Exhibition | A18 |
THPEA016 | The effects of prebiotics on microbial dysbiosis, butyrate production and immunity in HIV-infected subjects | Poster Exhibition | A30 |
THPEA017 | Sirtuin1 inhibitor nicotinamide disrupts HIV-1 latency | Poster Exhibition | A44 |
THPEA018 | Thalidomide reverses latency of HIV-1 provirus | Poster Exhibition | A44 |
THPEA019 | Targeting HSF1-mediated stress response can enhance Hsp90 inhibitor-induced suppression of HIV-1 reactivation from latency | Poster Exhibition | A44 |
THPEA020 | A novel assay to evaluate the response of patient-derived virus to latency-reversing agents ex vivo | Poster Exhibition | A44 |
THPEA021 | Therapeutic immune recovery prevents emergence of CXCR4-tropic HIV-1 | Poster Exhibition | A44 |
THPEA022 | Dendritic cells programmed by inflammatory mediators can effectively induce both the immunologic 'kick' and 'kill' of latent HIV-1 | Poster Exhibition | A44 |
THPEA023 | Association of the chemokine stromal-derived factor-1 (SDF-1) genetic polymorphism with transaminitis in HIV-infected Thais who are on combined antiretroviral therapy | Poster Exhibition | A46 |
THPEA024 | Optimal resource allocation of a female sex workers HIV prevention interventions across districts of different size and prevalence | Poster Exhibition | A46 |
THPEA025 | A novel bispecific immunoadhesin displays enhanced breadth and potency against diverse HIV-1 subtypes in vitro and in humanized mice | Poster Exhibition | A56 |
THPEA026 | Evolution of cross-neutralizing antibodies and mapping epitope specificities in plasma of chronic HIV-1 infected ART naïve children from India | Poster Exhibition | A58 |
THPEA027 | Molecular characteristics and use of bovine IgG with broad HIV-1 neutralizing activity from colostrum of cows vaccinated with Env-gp140 trimers | Poster Exhibition | A58 |
THPEA028 | Intranasal vaccination with a live recombinant rhinovirus and a DNA boost elicits HIV-specific immunity that controls EcoHIV infection in mice | Poster Exhibition | A61 |
THPEA029 | HIV-tat fused to the oligomerisation domain of the c4-binding protein is highly immunogenic and controls EcoHIV challenge in mice | Poster Exhibition | A62 |
THPEA030 | Introducing the new fully-automated volumetric Aquios flow cytometer PanLeucogate (PLG) platform for CD4-T lymphocyte enumeration in South Africa. Part I: establishing instrument precision and accuracy | Poster Exhibition | A70 |
TUAA0101 | Microbial translocation during hyperacute SIV infection | Oral Abstract | A27 |
TUAA0102 | Impact of a fat-rich diet on the pathogenesis of SIV infection in the African green monkey host | Oral Abstract | A27 |
TUAA0103 | HIV infection is associated with preservation of MAIT cells in the lungs but alteration of their phenotype and T cell receptor repertoire | Oral Abstract | A12 |
TUAA0104 | Cell-associated HIV-1 unspliced RNA level predicts both time to virological suppression and duration of post-treatment virological control in patients treated with temporary early ART | Oral Abstract | A40 |
TUAA0105 | HIV-infected patients with exceptional TCD4+ recovery during effective HAART present a distinct T CD4+ differentiation pattern, higher CD31neg naïve cells and a smaller HIV reservoir | Oral Abstract | A20 |
TUAA0106LB | Dysbiotic bacteria drive suppressive neutrophil phenotypes and prolonged lifespan in mucosal tissues of HIV-infected individuals | Oral Abstract | A28 |
TUPDA0101 | Selection of HIV-1 variants with higher transmission potential by 1% tenofovir gel microbicide | Poster Discussion Abstract | A50 |
TUPDA0102 | Characterization of HIV-1 genomes from 74 acutely infected subjects in the acute infection cohort RV217 | Poster Discussion Abstract | A50 |
TUPDA0103 | HIV-associated alteration in gut microbiota are associated with increased inflammation and infection of enteric CD4+ T cells | Poster Discussion Abstract | A28 |
TUPDA0104 | The association of injectable progestin-only contraceptives and endogenous progestins with HIV target cell frequency in the cervix and HIV acquisition risk | Poster Discussion Abstract | A24 |
TUPDA0105 | The mechanisms and role of HPV in enhancing HIV transmission in women in South Africa | Poster Discussion Abstract | A68 |
TUPDA0106 | The endotoxin-lipoprotein hypothesis, obesity and HIV | Poster Discussion Abstract | A27 |
TUPEA001 | RANTES, CD169/Siglec-1 and CD38-HLADR are independently associated with CXCR4-tropism in treatment naïve HIV-1 subtype C infected individuals | Poster Exhibition | A24 |
TUPEA002 | CD4+ T cell activation: a new link between intimate partner violence and HIV risk? | Poster Exhibition | A24 |
TUPEA003 | The effect of HIV-1 infection on S1P-R1 expression and function in thymocytes and their progenitors during entry into and egress from the human thymus | Poster Exhibition | A25 |
TUPEA004 | Gamma-delta T cells phenotype and activation in HIV-infected treatment- naïve patients: correlation with disease stage and immunological response | Poster Exhibition | A25 |
TUPEA005 | Immunometabolic analysis identifies key role of hypoxia inducible factor-1 alpha (HIF-1α) in HIV-induced CD4+T cell depletion | Poster Exhibition | A25 |
TUPEA006 | Memory stem T cells and markers of mucosal immunity in the course of cART | Poster Exhibition | A25 |
TUPEA007 | Residual inflammation and endothelial activation in HIV-1 vertically infected children with fully suppressed viral replication on antiretroviral therapy | Poster Exhibition | A29 |
TUPEA008 | Identification of functional HIV-1 C envelope variants containing a phenylalanine residue at position 309 of the hypervariable region 3 in matched peripheral blood and cerebrospinal fluid | Poster Exhibition | A32 |
TUPEA009 | The impact of confounding factors on determination of biomarkers for neurocognitive disorders in HIV-infected subjects | Poster Exhibition | A33 |
TUPEA010 | Association between dual TIM-3 and PD-1 expressing CD4 T cells and neurocognitive function in chronic stable HIV disease | Poster Exhibition | A33 |
TUPEA011 | Post-treatment control or treated controllers? The impact of ART on time to viral rebound in recent seroconverters | Poster Exhibition | A36 |
TUPEA012 | Identification of different HIV-controller phenotypes: looking for the right model of functional cure | Poster Exhibition | A36 |
TUPEA013 | HIV virological controllers in an African cohort | Poster Exhibition | A36 |
TUPEA014 | Identification of a new host cell HDAC complex that controls HIV latency through direct binding to the core promoter | Poster Exhibition | A41 |
TUPEA015 | The influence of HLA-types on disease progression among HIV-2 infected patients in Guinea-Bissau | Poster Exhibition | A45 |
TUPEA016 | Mannose binding lectin genetic polymorphism: absence of an association with HIV-1 vertical transmission in a PMTCT cross-sectional survey in Zimbabwe | Poster Exhibition | A45 |
TUPEA017 | Serum estradiol level and subject age are associated with ex vivo HIV infection in human cervical tissue | Poster Exhibition | A47 |
TUPEA018 | HIV-1 constructs do not trigger macrophage inflammatory protein - 3 alpha secretion in human genital epithelial cell models | Poster Exhibition | A47 |
TUPEA019 | Dynamics of HIV and its target cells in the female reproductive track during acute infection and after therapy | Poster Exhibition | A47 |
TUPEA020 | Early reverse transcripts, an early indicator of cART efficacy in neonatal HIV | Poster Exhibition | A48 |
TUPEA021 | Acute HIV-1 infection in men who have sex with men attending the clinic for voluntary counseling and testing services in Bangkok, Thailand | Poster Exhibition | A51 |
TUPEA022 | Comparison of HIV epitopes availability between acute and chronic infection | Poster Exhibition | A51 |
TUPEA023 | Identification of a cytokine expression pattern specific for the first month of HIV infection | Poster Exhibition | A51 |
TUPEA025 | HIV pre-exposure prophylaxis for women and infants prevents vaginal and oral HIV transmission in a pre-clinical model of HIV infection | Poster Exhibition | A53 |
TUPEA026 | Evaluation of the loop-mediated isothermal amplification (LAMP) assay for the detection of M. tuberculosis (TB) in symptomatic tuberculosis patients attending a primary healthcare clinic (PHC) in Durban | Poster Exhibition | A66 |
TUPEA027 | High-risk human papillomavirus types in HIV-infected and uninfected young women in a cross-sectional study in KwaZulu Natal, South Africa: implications for vaccination | Poster Exhibition | A68 |
TUPEA028 | Transcriptome analysis of differentially expressed ISG subsets in acute and chronic phase suggests INFg participate in sustaining persistent ISG expression in pathogenic SIV infection in cynomolgus macaques | Poster Exhibition | A75 |
TUPEA029 | PNS inflammation during acute SIV | Poster Exhibition | A75 |
TUPEA030 | Distribution and localization of fluorescently tagged passively transferred antibodies: defining antibody dynamics and localization in vivo | Poster Exhibition | A76 |
WEAA0101 | Th17 cells are preferentially infected in the first 48 hours after vaginal transmission of SIVmac239 in macaques | Oral Abstract | A47 |
WEAA0102 | Effect of injectable hormonal contraceptives on vaginal epithelium thickness and genital HIV target cell density in women recently infected with HIV | Oral Abstract | A7 |
WEAA0103 | Characterization of early events of SIVagm dissemination following intrarectal inoculation in adult AGMs | Oral Abstract | A51 |
WEAA0104 | Early treatment of hyperacute HIV infection impacts phenotype and clonal repertoire of HIV-specific CD8+ T cells | Oral Abstract | A16 |
WEAA0105LB | Exhaustion of activated CD8 T cells predicts disease progression in primary HIV-1 infection | Oral Abstract | A29 |
WEAA0106LB | HIV Cure research in a novel population of South African hyper-acute HIV infections detected in the blood donation setting: the Monitoring and Acute Treatment of HIV Study (MATHS) | Oral Abstract | A51 |
WEPDA0101 | Novel mode of recognition of the glycan-V1V2 region of HIV-1 envelope by a new lineage of broadly neutralizing antibodies | Poster Discussion Abstract | A14 |
WEPDA0102 | Non-classical CD8+ T cells restricted by HLA class II emerge in HIV infection and show antiviral efficacy | Poster Discussion Abstract | A16 |
WEPDA0103 | Presence of HIV-1C broadly neutralizing antibodies in pregnancy and at delivery | Poster Discussion Abstract | A39 |
WEPDA0104 | PML/TRIM19-dependent inhibition of retroviral reverse-transcription by Daxx | Poster Discussion Abstract | A8 |
WEPDA0105 | Human sPD1-based HIV-1 gag-fusion DNA vaccine induces high frequency of broadly reactive T cell responses in mice and rhesus macaques | Poster Discussion Abstract | A59 |
WEPEA001 | Genetic variability of HIV-1 in the north-west of Benin, Africa: the rise of complex circulating recombinant form 30_0206 (CRF30_0206) | Poster Exhibition | A2 |
WEPEA002 | HIV-1 subtype-specific constraints on viral escape from host cellular immunity | Poster Exhibition | A2 |
WEPEA004 | Analysis of intra-patient, full length HIV gag sequences identifies regions of variability | Poster Exhibition | A2 |
WEPEA005 | Natural variation and co-variation of the HIV-1 integrase in drug-naïve newly diagnosed HIV-1 infections in Germany | Poster Exhibition | A3 |
WEPEA006 | Impact of Gag-protease mutations on viral fitness and drug susceptibility in HIV-1 subtype C infected patients failing a protease inhibitor inclusive treatment regimen from Durban, South Africa | Poster Exhibition | A3 |
WEPEA007 | HIV-1 groups M+O dual infections and HIV-1/MO recombinant forms circulating in Cameroon | Poster Exhibition | A5 |
WEPEA008 | Interferon-induced sterile alpha motif and histidine/aspartic acid domain-containing protein 1 (SAMHD1) expression is mediated by miR-181a | Poster Exhibition | A8 |
WEPEA009 | Endogenous TRIM5a function is regulated by SUMOylation and nuclear sequestration for efficient innate sensing in dendritic cells | Poster Exhibition | A8 |
WEPEA010 | HIV-1 CRF07_BC displays slow disease progression and delayed type of viral budding | Poster Exhibition | A21 |
WEPEA011 | Changes in Rev in HIV isolates from different clades have a significant impact on Rev/RRE functional activity | Poster Exhibition | A22 |
WEPEA012 | HIV-1 RNAs of the 1 kb class, splicing near the 3' end of the viral genome, lack coding capacity and enhance viral replication in peripheral blood mononuclear cells | Poster Exhibition | A22 |
WEPEA013 | Metabolic dependency of HIV-1 replication: glucose and glutamine metabolism in HIV-infected primary CD4+ T cells | Poster Exhibition | A23 |
WEPEA014 | Dependency of HIV-1 replication on and viral manipulation of the glycolytic metabolism of activated primary CD4+ T cells | Poster Exhibition | A23 |
WEPEA015 | Exploring the role of phosphorylation as regulatory mechanism induced by HIV-1 to favor virus replication | Poster Exhibition | A23 |
WEPEA016 | Human cytomegalovirus latent infection modulates HIV restriction factors in CD34+ hematopoietic stem cells | Poster Exhibition | A40 |
WEPEA017 | Memory CD4+ T cells expressing HLA-DR contribute to HIV persistence during prolonged ART | Poster Exhibition | A42 |
WEPEA018 | Is the lung a site of productive HIV infection that persists through ART? | Poster Exhibition | A42 |
WEPEA019 | Quantification and correlates of the replication competent HIV-1 latent viral reservoir in a virally suppressed Ugandan population | Poster Exhibition | A43 |
WEPEA020 | Therapy with the immunomodulatory agent pomalidomide does not lead to changes in HIV-1 viral populations in vivo | Poster Exhibition | A57 |
WEPEA021 | Novel pathways of Tat expression identify new targets for reactivation of latent HIV-1 | Poster Exhibition | A57 |
WEPEA022 | Combinatorial CRISPR/Cas9 approaches targeting different steps in the HIV life cycle can prevent the selection of resistance | Poster Exhibition | A57 |
WEPEA023 | Enhancing HIV-1 virion tethering by BST2/tetherin sensitizes productively and latently infected T cells to ADCC mediated by broadly neutralizing anti-HIV antibodies | Poster Exhibition | A57 |
WEPEA024 | Small molecule inhibitors of BAF: a new family of compounds in HIV-1 latency reversal | Poster Exhibition | A57 |
WEPEA025 | Novel activators and suppressors of latent HIV-1 from natural products | Poster Exhibition | A57 |
WEPEA026 | Heterodimeric IL-15 induces effector cell activation and trafficking to the Germinal Centers of SIV infected Macaques | Poster Exhibition | A57 |
WEPEA027 | Multisite evaluation of the BD FACSPresto? CD4 counter | Poster Exhibition | A69 |
WEPEA028 | Pilot assessment of the diagnostic accuracy of Cepheid GeneXpert HIV-1 Qual for early infant diagnosis | Poster Exhibition | A69 |