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Young women bear a disproportionate burden of the HIV epidemic in Africa. Reducing the high rates of HIV infection in young women is central to changing the trajectory of HIV in Africa. This session presents new findings from the CAPRISA consortium of researchers from South Africa and North America and sheds new light on why young women in Africa are at such high risk of acquiring HIV. This session is targeted towards HIV prevention researchers who are developing new HIV prevention technologies and those who are interested in understanding risk factors for HIV acquisition in young women. Participants will develop an understanding of who young women are predominantly acquiring their HIV infections from, why young women are at high risk of acquiring HIV and factors affecting pre-exposure prophylaxis in women. Implications for HIV prevention programs and proposed new interventions to reduce HIV rates in women in Africa will be presented.

14:30
TUSS0601
Opening remarks
Anthony Fauci, National Institutes of Health (NIH), United States
Deborah Birx, The U.S. President's Emergency Plan for AIDS Relief (PEPFAR), United States
14:32
TUSS0602
HIV infection in young women in Africa: An overview
Quarraisha Abdool Karim, Centre for the AIDS Programme of Research in South Africa (CAPRISA), South Africa
Slides

14:37
TUSS0603
Who is infecting who? Community-wide phylogenetic transmission networks reveal young women’s high HIV exposure from older men with low ART coverage
Tulio de Oliveira, University of KwaZulu-Natal, South Africa
David Khanyile, Epicentre, South Africa

14:49
TUSS0604
Role of vaginal microbiota in genital inflammation and enhancing HIV acquisition in women
Jo-Ann Passmore, University of Cape Town, South Africa
Brent Williams, Columbia University, United States

15:01
TUSS0605
Uncovering the role of the vaginal microbiome in undermining PrEP efficacy in women
Adam Burgener, Public Health Agency of Canada, Canada
Nichole Klatt, University of Washington, United States

15:14
TUSS0606
Understanding high rates of HIV in young women in Africa: Implications of new epidemiological, phylogenetic, genomic and proteomic evidence
Salim Abdool Karim, Centre for the AIDS Programme of Research in South Africa (CAPRISA), South Africa

15:19
TUSS0607
Remarks by Session Co-Chairs in opening Q&A
Anthony Fauci, National Institutes of Health (NIH), United States
Deborah Birx, The U.S. President's Emergency Plan for AIDS Relief (PEPFAR), United States
15:20
TUSS0608
Q&A